Katherine Heigl & T.R. Knight Leaving Grey’s Anatomy Regan Cellura February 10, 2009 Greys Anatomy 20 Comments It had been widely reported that Grey's Anatomy's T.R. Knight had asked to be released from his contract with the show. When Dr. Izzie Stevens started seeing her dead fiance due to an illness, many speculated that Katehrine Heigl would be following Knight out the door. Heigl and Knight's co-star, James Pickens Jr. has confirmed to Us Weekly that both actors are indeed leaving Seattle Grace behind. "Yes, she is," Pickens told Us Weekly when asked if Heigl is leaving the ABC hospital drama. "Wherever Katherine goes, I wish her nothing but the best." Her outspoken BFF, Knight, 35. "He's going too," Pickens told Us at the NAACP Awards luncheon in Beverly Hills. "He just wanted to pursue other career paths."