- Jennifer Landon (ex-Gwen) will recur on FBI: Most Wanted
- Lesley-Anne Down (ex-Jackie) appears as British Prime Minister Margaret Thatcher in the upcoming Ronald Reagan biopic Reagan
- Wayne Brady (ex-Reese) will guest star in the pilot for Showtime's American Gigolo
- Sean Kanan (ex-Deacon) will appear in More Than Miyagi, a documentary about Karate Kid star Pat Morita, available Feb. 5
- Marc Anthony Samuel (Felix) is one of the narrators of the audiobook A Father's Sacrifice by Ben Burgess, Jr.
- Johnny Wactor (Brando) appears in the 2021 "Helping Protect" ad for Gardasil
- Kelli Barrett (ex-Maddie) will participate with husband Jarred Spector in two showings of a limited-capacity, distanced performance of Funny How It Happens: A Valentine's Day Celebration, taking place Feb. 14 at The Ridgefield Playhouse at 4 PM and 8 PM
- Kristian Alfonso (ex-Hope) and Alison Sweeney (Sami) will star, as previously announced, in Hallmark's Chronicle Mysteries: Helped to Death; Alfonso revealed on Instagram the film will air Feb. 21 and shared the trailer
- Nathan Fillion (ex-Joey) has lent his voice to a virtual forest tour for Alberta Forest Products Association (AFPA)
- Judith Light (ex-Karen) stars in the musical Tick, Tick...BOOM!, coming to Netflix in 2021
- Mark Wystrach (ex-Fox) stars in the Tammy Faye Bakker biopic The Eyes of Tammy Faye, premiering Sept. 24
- Eva Longoria (ex-Isabella) has joined the cast of the all-star anthology Women's Stories; her segment, Lagonegro, will be directed by Lucia Puenzo
